We've seen a few requests for something like this, and so here it is. We have a list here of when and how you might want to consider taking a card in draft. Here are the tiers we're using:

• Tier I - Your first pick. If you see it, take it. This will synergize well with multiple cards that you will see and/or basic actions that you can bring. If you have multiple high-tier picks, you must choose based on the type of team you want to build.
• Tier I.a - May be your first pick in hand one  if you plan on executing a specific strategy. More highly dependent on the rest of your deck. This pick may especially  be informed by evaluating the cards you open in hand one and hand two and how they might synergize. 
• Tier II - Early picks. Could be a first pick, can be built around, but hopefully it isn't.
• Tier III - Take these after options in I and II are exhausted. These are high-quality playable cards; supporting characters for the strategies above. 
• Tier IV - Playable cards. They're not amazing, but they're solid performers. These should match the energy types that you need. 
• Tier V - Situational cards. Only take these if your deck will benefit or if your meta requires the ability that they bring. 
• Tier VI - Avoid. Don't take these, or if you're forced to, it probably shouldn't be in your deck unless you have severe energy or role deficiencies.  

The cards are listed alphabetically (mostly) and are not in any particular order of strength within the tiers.

This is not 100% foolproof. No one will ever 100% agree with the list. It's just not possible, especially in a game where so many cards have such a high dependency on other cards. We at TRP have a few disagreements amongst ourselves with the placement of things on this list. What it does do is generate discussion, and that's very important.

UXM Draft Priority List